Breast Cancer Risk Elevated In Male BRCA Mutation Carriers

Men with mutations in the BRCA1 or BRCA2 genes are at greater risk of breast cancer than the general population. Male breast cancer accounts for less than 1 percent of all breast cancers in the U.S., and it is most common in men with a family history of the disease. Previous studies have shown that men who carry mutations in the BRCA2 gene have a greater risk of developing breast cancer than men in the general population. The association between BRCA1 mutations and breast cancer in men was less clear.