Research In Lung Cancer Provides New Insights

Reports from the United States highlight recent research on lung cancer. Study 1: Cytochrome P450 (CYP)1A1 and CYP1B1 polymorphisms were linked to lung cancer risk. According to recent research published in the journal Carcinogenesis, "The CYP superfamily of enzymes catalyze one of the first steps in the metabolism of carcinogens such as polycyclic aromatic hydrocarbons, nitroaromatics and arylamines. Polymorphisms within the CYP1A1 gene have been shown to be associated with lung cancer risk, predominantly among Asian populations." "Despite functional evidence of a possible role of CYP1B1 in lung cancer susceptibility, only a few studies have evaluated polymorphisms in this gene in relation to lung cancer susceptibility. This popul...