Ovarian Cancer Treatment By Treosulfan And Carboplatin Compared

Ovarian cancer treatment by treosulfan and carboplatin was compared. According to recent research from Scotland, "The management of older and unfit women with advanced ovarian cancer requires postoperative chemotherapy but many of these patients are not suitable for high-dose cisplatin-based regimes. Carboplatin has been an easier alternative and can be given in the ambulatory setting." "Historical data suggests that oral alkylating agents to be just effective with similar efficacy. In this study we have compared platinum-based carboplatin to the alkylating agent treosulfan in a population unfit to receive high-dose cisplatin. The trial randomised patients to either intravenous carboplatin or treosulfan as single agent. The trial was...