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General Health

Information and news articles regarding the subject of general health.

New light on the mechanism of Parkinson’s disease

A significant number of Parkinson’s disease patients have a mutation of the enzyme Leucine-Rich Repeat Protein Kinase 2 (LRRK2, also known as dardarin). However, little is understood about how it is regulated or functions. In a new paper, researchers demonstrate that a family of proteins, the 14-3-3 proteins, interact with LRRK2.

New model to measure disease burden of postmenopausal osteoporosis

Researchers report the development of a validated new model that can be used to forecast the current and future burden of postmenopausal osteoporosis in different national settings.

Critical 'traffic engineer' of the nervous system identified

Scientists have identified a critical enzyme that keeps traffic flowing in the right direction in the nervous system, and the finding could eventually lead to new treatments for conditions such as Alzheimer's and Parkinson's disease.

Single gene regulates motor neurons in spinal cord

In a surprising and unexpected discovery, scientists have found that a single type of gene acts as a master organizer of motor neurons in the spinal cord. The finding could help scientists develop new treatments for diseases such as Lou Gehrig's disease or spinal cord injury.

Investigating better endpoints for immunotherapy trials

Cancer immunotherapy calls for revised clinical endpoints that differ from those used for chemotherapy, according to a new article.

Why the biological clock? Aging reduces centromere cohesion, disrupts reproduction, biologists discover

Biologists studying human reproduction have identified what is likely the major contributing factor to the maternal age-associated increase in aneuploidy, the term for an abnormal number of chromosomes during reproductive cell division.

Interneurons are not all created equally: Some classes of interneurons may underlie distinct brain disorders

A type of neuron that, when malfunctioning, has been tied to epilepsy, autism and schizophrenia is much more complex than previously thought, researchers report.

More accurate method of determining premature infants' risk of illness

Researchers have developed a revolutionary, noninvasive way of quickly predicting the future health of premature infants, an innovation that could better target specialized medical intervention and reduce health-care costs.

Short sleepers at higher risk of type 2 diabetes and heart disease, study finds

People who sleep less than six hours a night may be three times more likely to develop a condition which leads to diabetes and heart disease, according to researchers.

Multivitamin use doesn't impact colon cancer outcomes, study finds

Patients with colon cancer who used multivitamins during and after being treated with post-surgical chemotherapy did not reduce the risk of the cancer returning or their dying from it, according to researchers. In a study of 1,038 patients with stage III colon cancer, the researchers found that while multivitamin use had no beneficial effect on patients' outcomes, it also did not have a detrimental effect.

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