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A second Phase I AIDS vaccine clinical trial in India was successfully completed, the Indian Council of Medical Research, the National AIDS Control Organization and the International AIDS Vaccine Initiative announced. The results of the trial of an MVA-based AIDS vaccine candidate (TBC-M4), which was conducted in Chennai, indicated that the vaccine candidate had acceptable levels of safety and was well-tolerated.

People taking prescription antidepressants appear to drive worse than people who aren't taking such drugs, and depressed people on antidepressants have even more trouble concentrating and reacting behind the wheel.

Robert Linhardt has spent years stitching together minuscule carbohydrates to build a more pure and safer alternative to the commonly used and controversial blood thinner heparin. Now he has announced that his research team may have accomplished this task by building the first fully synthetic heparin. Their creation is the largest dose of heparin ever created in the lab.

Scientists have known for decades that genes called transposons can jump around the genome in a cell. This jumping can be dangerous, especially when it arises in cells that produce eggs and sperm. Although nature developed a mechanism to quash this genetic scrambling, how it works has remained a mystery. Now scientists have identified a key protein that suppresses jumping genes in mouse sperm and found that the protein is vital to sperm formation.

A new study in CMAJ has found that, despite the possibility of shorter waiting times for surgery, a majority of patients were unlikely to consider changing surgeons.

A large genetic study of bipolar disorder has implicated machinery that balances levels of sodium and calcium in neurons. The disorder was associated with variation in two genes that make components of such ion channels. Although it's not yet known if or how the suspect genetic variation might affect the balance machinery, the results point to the possibility that bipolar disorder might stem, at least in part, from malfunction of ion channels.