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According to new research many drugs are approved on the brink of FDA deadlines, and these drugs are more likely to later face regulatory intervention for safety reasons. Drugs fast-tracked by the FDA are more likely to eventually be withdrawn from global markets for safety reasons, undergo manufacturing revisions, or face labeling changes.

A new study suggests salmonella strains collected from human salamonellosis patients to be distinct from those of animal origin, a finding that could significantly impact the development of treatment methods for foodborne illnesses. Salmonella enterica, one of the most infectious foodborne pathogens inflicting humans today, is commonly transmitted through consumption of meat and food products that have been contaminated with animal waste.

What is believed to be the largest study of its kind for the genetic roots of inflammatory bowel diseases has suggested new links to Crohn's disease as well as further evidence that some people of Jewish descent are more likely to develop it.

A novel strategy based on targeted immune suppression using human umbilical cord blood cells may improve the pathology and cognitive decline associated with Alzheimer's disease, based on the results of a study in a mouse model of this currently untreatable neurodegenerative condition, as described in a groundbreaking report in Stem Cells and Development.

Here's a maxim from the "duh" department: People typically prefer to feel emotions that are pleasant, like excitement, and avoid those that are unpleasant, like anger. But a new study appearing in Psychological Science says this may not always be the case.

Mercury is a large component of dental fillings, but it is not believed to pose immediate health risks in that form. When exposed to sulfate-reducing bacteria, however, mercury undergoes a chemical change and becomes methylated, making it a potent, ingestible neurotoxin.

Beta-blockers heal the heart via the brain when administered during heart failure, according to a new study. Up to now, it was thought that beta-blockers work directly on the heart, but the new study shows that the drugs may also act via the brain, suggesting that future therapies to treat cardiovascular disease could be targeting the central nervous system.

Pollution from coal mining may have a negative impact on public health in mining communities. "Residents of coal-mining communities have long complained of impaired health," and researchers say "This study substantiates their claims. Those residents are at an increased risk of developing chronic heart, lung and kidney diseases."

Hormonal contraception may become a safe, effective, and reversible form of birth control for men, according to a new study. The study revealed that the combination of testosterone and progestin suppressed sperm production faster and more completely than testosterone alone. "It is possible to suppress sperm output to concentrations that are comparable with reliable contraception in most, but not all men," said the lead author of the study. "The rate of suppression is comparable to that achieved after a vasectomy."

An increased number of neuron "hubs" in the epileptic brain may be the root cause for the seizures that characterize the disorder, according to a new study. Scientists have identified that these hubs -- a small number of highly connected neurons -- are formed in the hippocampus during the transition from a healthy brain to an epileptic one.