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Only two percent of pediatric drug trials reported using independent safety monitoring committees that can help lead to the early detection of adverse drug reactions, according to a major review. Seven out of ten trials reported adverse events and a fifth of the trials reported a serious adverse event, ie. an untoward medical occurrence, not necessarily related to a drug. Adverse drug reactions were reported in just under 37 per cent of trials, with 11 per cent of trials reporting moderate or severe adverse drug reactions.

Over the past 35 years the proportion of foodborne outbreaks linked to the consumption of leafy green vegetables has substantially increased and that increase can not be completely attributed to Americans eating more salads according to new research.

Children with an inherited blood disorder called alpha thalassemia make unusually small red blood cells that mostly cause a mild form of anemia. Now, researchers have discovered that this disorder has a benefit -- it can protect children against one of the world's greatest killers, malaria, according to a new study.

Scientists have developed a new mouse model to help illuminate the vagaries of autism, according to a study from a Stanford University School of Medicine researcher and other colleagues. The study focused on mice missing the gabrb3 gene, which codes for a protein important in brain development and normal adult brain function

Botox, is best known as one of the most commonly used molecules to reduce wrinkles. It is also known as one of the most poisonous naturally occurring substances. Now, after new research, it has become an effective method to save newborns suffering from CHARGE Syndrome from devastating tracheotomies.

If the battle against HIV, the virus that causes AIDS, is a chess match, then new research published today gives new insight into one of the virus' most important moves. The findings reveal information about how a critical genetic switch in the virus operates. When HIV infects an immune cell, it can enter one of two states: activation, where the virus replicates and then destroys the host cell; and latency, where the viral genetic material continues to exist in the cell, but there is no production of additional virus.

Researchers have found a process in the brain that may help explain the link between Alzheimer's and stroke. This finding connects the dots between a peptide called p25 and increased production of amyloid beta. This newly identified p25/cdk5 pathway could explain why the risk of Alzheimer's disease is significantly higher following a stroke.

Researchers have estimated that one in six women are at risk for developing Alzheimer's disease in their lifetime, while the risk for men is one in ten. Stroke and dementia are the most widely feared age-related neurological diseases, and are also the only neurological disorders listed in the ten leading causes of disease burden.

Researchers have identified four separate biochemical subgroups in a selection of cases of Creutzfeldt-Jakob disease. The study suggests that these subgroups could represent distinct prion strains in what is the most common human prion disease.

Doctors may one day be able to detect early stages of colon cancer without a biopsy, using a new technique. The imaging technology is one of many new ways of detecting cancers in the body in real time.