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Gene Therapy: Polymer Translocation Pulled through a Narrow Pore

When polymeric molecules squeeze through a nanometer-sized pore in membranes, in a process known as translocation, they leave a distinct signature at the pore. Present-day techniques can exploit translocation to recognize individual polymeric molecules by analyzing these signatures.

Researchers May Have Found Test For Depression

Researchers have discovered that a change in the location of a protein in the brain could serve as a biomarker for depression, making it possible with a simple, rapid, laboratory test to identify patients with depression and to determine whether a chosen antidepressant therapy will provide a successful response.

Obese Women Gain Too Much Weight During Pregnancy, Expert Says

Heavy women gain too much weight during pregnancy, says an obstetrician and obesity expert. Recommendations which are followed worldwide by obstetricians, encourage obese women to gain at least 15 pounds during pregnancy and specify no upper limit for weight gain. Overweight or obese women don't need to gain that much weight and should exercise and watch their calorie consumption during pregnancy, according to a new editorial.

One In Four Teenage Girls In U.S. Has Sexually Transmitted Disease, CDC Study Shows

A new CDC study estimates that one in four (26 percent) young women between the ages of 14 and 19 in the United States -- or 3.2 million teenage girls -- is infected with at least one of the most common sexually transmitted diseases (human papillomavirus (HPV), chlamydia, herpes simplex virus, and trichomoniasis). The two most common STDs overall were human papillomavirus, or HPV (18 percent), and chlamydia (4 percent). Data were based on an analysis of the 2003-2004 National Health and Nutrition Examination Survey.

New Method May Revolutionize Diabetes Research

Scientists have developed a method for studying complicated cell processes, such as the secretion of insulin in the pancreas, of living animals -- something that has not been possible to this date. The new method, which involves the transplantation of a tiny part of the pancreas onto the iris of mice, paves the way for radical approaches to diabetes research, which has previously been conducted on single cells in artificial laboratory environments.

First Early-detection Blood Test For Parkinson's Shows Promise

A test that profiles molecular biomarkers in blood could become the first accurate diagnostic test for Parkinson's disease, new research shows. The screen relies on changes in dozens of small molecules in serum. These "metabolomic" alterations form a unique pattern in people with Parkinson's disease.

Life Expectancy Rises For The Educated; The Less-educated Reap No Benefit

While life expectancy has increased significantly for educated people over the last twenty years, it has plateaued for less educated people. In other words, those whose education level does not exceed high school have not been sharing the benefits of prolonged lifespan. This is the case for both African Americans and Caucasians. Deaths related to tobacco use account for at least one-fifth of the growth in mortality differences by education that create this life expectancy gap.

Herb Anise Contains Unique Healthful Phenylpropanoids, Study Suggests

People use anise to add a hint of licorice to everything from holiday cookies to robust bottles of ouzo and raki. Now plant pathologists have found that anise (Pimpinella sp.) is more than just another jar in the spice rack. Researchers have isolated 22 compounds in Pimpinella's essential oils and found high levels of organic mixtures called phenylpropanoids. Phenylpropanoids are found in a wide variety of plants, and some are thought to have health-boosting benefits. However, the chemical structure and biological activity of the Pimpinella phenylpropanoids are unique.

Advanced-stage Ovarian Cancer Patients With BRCA Live Longer, May Respond Better To Treatment, Study Shows

Two abstracts underscoring the importance of testing for BRCA1/2 mutations in women with ovarian cancer have recently been presented. The majority of women with ovarian cancer are unaware BRCA testing is available.

Epigenetic Changes Discovered In Major Psychosis

Scientists at the Center for Addiction and Mental Health have discovered epigenetic changes in individuals with schizophrenia and bipolar disorder. This is the first epigenome-wide investigation in psychiatric research, and this groundbreaking data may be a significant step on the journey to fully understanding major psychosis.

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