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HealthGrades, the nation's leading independent healthcare ratings organization, today identified America's 50 Best Hospitals, an elite class of top-performing facilities. The HealthGrades America's 50 Best Hospital designation represents the healthcare industry's only quality ranking based solely on objective clinical outcomes among US hospitals.

The focus of two recent Nobel prizes, a species of roundworm has made possible another advance in the understanding of how cells talk to one another. A new mechanism through which cells in the worm's intestine signal for nearby muscle cells to flex by briefly making the area between them more acidic has been discovered. Researchers believe that short-lived changes in acidity may have implications for cell signaling throughout the animal kingdom, from the sending of human nerve messages to worm defecation.

While pondering the challenges of distinguishing one nano-sized probe image from another in a mass of hundreds or thousands of nanoprobes, researchers made an interesting observation. The tiny, clustered dots of light looked a lot like a starry sky on a clear night. The biomedical researchers realized that astronomers had already made great strides in solving a problem very similar to their own — isolating and analyzing one dot (in this case a star) in a crowded field of light.

Patients suffering from fibromyalgia could benefit significantly from regular exercise in a heated swimming pool, a study in Arthritis Research & Therapy shows. The findings suggest a cost effective way of improving quality of life for patients with this often-debilitating disorder.

Chemists have developed a new technique harnessing the power of nanotechnology to help doctors identify and treat bacterial infections in record time. Research shows identification can happen in a few hours instead of days. As more bacterial strains resistant to many drugs emerge, it becomes more critical to quickly identify infections and the antibiotics that would most effectively treat them. Such quick identifications become even more important during epidemics because large numbers of samples would have to be tested at once.

A new study on effects of mobile phone radiation on human skin strengthens the results of the human cell line analyses: living tissue responds to mobile phone radiation. Earlier studies have shown that mobile phone radiation alters protein expression and activity in human endothelial cell line. This new study is unique, because for the first time it has examined whether a local exposure of human skin to RF-EMF will cause changes in protein expression in living people.

Pretty soon your gym gear will be more high tech than the groaning treadmill beneath you. Smart textiles and wearable devices can monitor your vital signs as you go about daily life. These clever clothes already exist and look set to find a market niche especially in elite sport and healthcare, say European researchers. And who stands to benefit most from these clever clothes? People with heart conditions or undergoing rehabilitation that require constant monitoring, athletes, newborns and people with sleep apnea are among the potential users.

Many studies on cocaine addiction - and attempts to block its addictiveness - have focused on dopamine transporters, proteins that reabsorb the brain's "reward" chemical once its signal is sent. Since cocaine blocks dopamine transporters from doing their recycling job, it leaves the feel-good chemical around to keep sending the pleasure signal. Now a new study suggests that cocaine's effects go beyond the dopamine system. In the study, cocaine had significant effects on brain metabolism, even in mice that lack the gene for dopamine transporters.

A new anti-cancer agent that targets breast cancer can overcome resistance to cancer drugs, according to a new study. Many tumours that are initially responsive to chemotherapy can develop resistance to it, allowing the cancer to progress. Studies have shown that one of the key reasons for the development of resistance is a protein pump called P-glycoprotein. Resistant cancer cells express P-glycoprotein and this removes anti-cancer drugs from the cell before they are able to kill the cell.

Add this to the growing list of health challenges faced by obese children: A new study finds that obese children are much more likely than normal-weight children to have problems with airway obstruction and other breathing-related functions during surgery.