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Selective Reporting Of Antidepressant Trials Exaggerates Drug Effectiveness, Report Finds

Selective publication in reporting results of antidepressant trials exaggerates the effectiveness of the drugs, according to a new report. Researchers examined reviews from the Food and Drug Administration (FDA) for trials of 12 widely prescribed antidepressant drugs approved between 1981 and 2004, involving 12,564 patients. Whether and how the studies were published depended on how they turned out, they found.

Vital New Light Shed On Iron Overload Disorder

Hereditary hemochromatosis is much more common than previously thought. A new article will spur more study to determine who is most likely to develop complications from the debilitating and potentially fatal disease.

Calcium Supplements May Increase Heart Attacks In Older Women

New research suggests that calcium supplements may increase the risk of heart attack in healthy postmenopausal women. Calcium supplementation is commonly prescribed to postmenopausal women to maintain bone health, and some data suggest that it might protect against vascular disease by lowering levels of bad cholesterol in the blood. But evidence for this theory is lacking, so researchers investigated the effect of calcium supplementation on heart attack (myocardial infarction), stroke, and sudden death.

Post Traumatic Stress Has Tripled Among Combat-exposed Military Personnel

There has been a threefold increase in new cases of self reported post-traumatic stress disorder symptoms among combat-exposed military personnel since 2001, according to a new study. Concerns have been raised about the health impact of military deployment. Studies have estimated as many as 30% of Vietnam War veterans developed post-traumatic stress disorder at some point following the war and, among 1991 Gulf War veterans, as many as 10% were reported to have post-traumatic stress disorder symptoms years after returning from deployment.

Genes Key To High Liver Cancer Rates In Men

A fundamental difference in the way males and females respond to chronic liver disease at the genetic level helps explain why men are more prone to liver cancer, according to researchers.

Psoriasis Drug Effective In Children And Adults, Study Suggests

College student Maria Anichini no longer has to hide her skin under long sleeves and pants. Her skin and life have rebounded since she became part of a trial testing an injectable drug for children and adolescents with psoriasis, a common skin disease causing red scaly patches all over the body. Researchers report the drug etanercept -- FDA approved for adults but never before tested in children for psoriasis-- dramatically reduced psoriasis flare-ups.

Some Wood Floor Finishes Are A Likely Source Of PCB Exposure

Old wood floor finishes in some homes may be an overlooked source of exposure to the now banned environmental pollutants polychlorinated biphenyls (PCBs). PCBs are persistent organic pollutants identified worldwide as human blood and breast milk contaminants. PCBs were banned in the 1970s because of their high toxicity.

Blood Test Can Gauge Prostate Cancer Risk, Study Shows

New genomics research has found that a simple blood test can determine which men are likely to develop prostate cancer. Researchers at found that five genetic variants previously associated with prostate cancer risk have a strong cumulative effect. Researchers found that a man with four of the five variants has an increased risk of 400 to 500 percent compared to men with none of the variants. The researchers then added a family history of prostate cancer to the equation -- for a total of six risk factors. A man with at least five of the six factors had increased risk of more than 900 percent.

Should Children Be Permitted To Get Genetic Testing For BRCA 1/2 Mutations?

It's an ethical dilemma with serious implications. Should children be tested for gene mutations that predispose them to developing breast cancer and/or ovarian cancer later in life? New research suggests the next generation of parents may support testing minors even when any steps to reduce that risk will be postponed until adulthood -- a finding that challenges current policies.

Genetic Differences May Help Explain Response To Multiple Sclerosis Treatment

By comparing the DNA of patients with multiple sclerosis whose symptoms are reduced by interferon beta therapy to the DNA of those who continue to experience relapses, researchers may have identified important genetic differences between the two, according to a new article. These differences could eventually be used to help predict which treatments will help which patients.

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