Men with mutations in the BRCA1 or BRCA2 genes are at greater risk of breast cancer than the general population. Male breast cancer accounts for less than 1 percent of all breast cancers in the U.S., and it is most common in men with a family history of the disease. Previous studies have shown that men who carry mutations in the BRCA2 gene have a greater risk of developing breast cancer than men in the general population. The association between BRCA1 mutations and breast cancer in men was less clear.



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