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Medivation, Inc. announced that its selective androgen receptor modulator, MDV3100, to date has reduced serum levels of prostate specific antigen (PSA), a marker of tumor growth, in the six patients enrolled in the first two dose groups of its ongoing Phase 1-2 trial in hormone refractory prostate cancer. PSA declines were seen in a dose-dependent manner in these patients. In the lowest dose group, after two months of treatment PSA levels declined 45 percent to 66 percent. PSA levels in the second lowest dose group declined 75 percent to 89 percent after the first month of treatment.

Men who consume more broccoli or cauliflower have a lower risk of prostate cancers that have spread beyond the prostate. Researchers tracked more than 29,000 men in the Prostate, Lung, Colorectal and Ovarian Cancer Screening Trial. After four years, the risk of advanced prostate cancer (stage III or IV) was roughly half as high for those who ate broccoli or cauliflower more than once a week than for those who ate those vegetables less than once a month. The researchers found no link with fruit, tomatoes, orange vegetables, beans, tofu, onions, or garlic.

For the third year in a row, the federal government received failing grades in Lung Cancer Alliance's (LCA) Annual 2007 Report Card, issued today to mark the start of Lung Cancer Awareness Month.

Breast cancer survivor Judy English used a new test to see if she needed chemotherapy. Judy English was prepared to take chemotherapy if it reduced the risk of breast cancer returning after surgery. "I didn't want to go through this again," said English, diagnosed with breast cancer in 2006. "I wanted to do everything possible to increase my chances of disease-free survival." But she didn't want to undergo chemotherapy and the serious side effects -- hair loss, nausea, vomiting and increased risk for leukemia and heart problems -- if it wasn't going to make a difference.

WEST LAFAYETTE, Ind. -- Pre-malignant mammary lesions in dogs and humans display many of the same characteristics, a discovery that could lead to better understanding of breast cancer progression and prevention for people and pets, said a Purdue University scientist from the School of Veterinary Medicine. A group of scientists including Sulma Mohammed have found similarities between benign lesions that are considered to carry risk for developing breast cancer in both canines and humans. Breast cancer is the second leading cause of cancer deaths in women.